Dr. Mitalipov on His Breakthrough Paper That Describes Editing Human Embryos With CRISPR/Cas9

Dr. Shoukhrat Mitalipov and other scientists discuss the recent breakthrough paper Dr. Mitalipov and his international team published in Nature on Wednesday which describes how they used the CRISPR/Cas9 gene editing tool to successfully repair inherited conditions in human embryos for the first time.

Dr. Shoukhrat Mitalipov is an American biologist who heads the Center for Embryonic Cell and Gene Therapy at the Oregon Health & Science University in Portland. He is known for discovering a controversial genetic therapy that may be a way to prevent mitochondrial diseases, as well as a new way of creating human stem cells from skin cells.

In July 2017, Mitalipov and his team performed the first known successful attempt at creating genetically modified human embryos, using the CRISPR/Cas9 gene modifying tool. Previously, there were only three reports of editing human embryos, which were all published by scientists in China.

Mitalipov and his team experimented upon a larger number of embryos, and further demonstrated the possibility of safely and efficiently correcting defective genes that cause inherited diseases.

The discussion took place on August 3rd, 2017

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